Ka lero la gastric ea motho, BPC 157 e tsitsitse ho feta lihora tse 24, kahoo e na le bioavailability e ntle ea molomo (kamehla e fanoang e le mong) le liphello tse molemo karolong eohle ea mala.Ena ke phapang ea bohlokoa ho tsoa ho li-peptide tse ling tse tloaelehileng, tse itšetlehileng ka ho eketsoa ha mokelikeli kapa li senngoa ka potlako ka lero la gastric ea motho.Re fana ka maikutlo a hore monehelo oa BPC 157 ho Robert's cytoprotection - ke hore, bokhoni ba ho loantša maqeba a ka mpeng a bakoang ke joala, ao Robert a ileng a a bitsa cytoprotection - le bokhoni ba ho loantša maqeba a bakoang ke ho kopana ho kotsi ka ho toba ha moemeli ea kotsi ka sele. e emela kgokelo ya peripheral pakeng tsa mala le mokoloko wa boko.
Perovic o tlalehile hore BPC 157 e na le phello e hlakileng ea phekolo e amanang le ho hlaphoheloa ha likhoto tse nang le leqeba la mokokotlo le mohatla o shoeleng litho (1-minute compression ea lesapo la mokokotlo oa sacrocaudal [S2-Co1]).Ka ho khetheha, tsamaiso e le 'ngoe ea intraperitoneal BPC 157 ka metsotso ea 10 ka mor'a kotsi e hanyetsa liphello tse mpe.Ka lehlakoreng le leng, lesapo la mokokotlo le ho holofala ha mohatla li tsoela pele ho likhoto tse sa phekoleheng, matsatsi a hlahlobiloeng, libeke, likhoeli le selemo ka mor'a kotsi.Ela hloko, BPC 157 e fokotsa tšenyo e atisang ho bakoa .Ka hona, phekolo ea BPC 157 e fella ka ho hlaphoheloa ho totobetseng, microscopic, le electrophysiologic.
Ela hloko, ho likhoto tse nang le kotsi ea lesapo la mokokotlo, ho na le reperfusion e sa feleng.Hang ha BPC 157 e tsamaisoa ka metsotso ea 10 ka mor'a kotsi ea khatello, ho na le tšireletso e tsoelang pele 'me ha ho na mathata a bakoang ke kotsi ea mokokotlo oa mokokotlo hape.
Kahoo, ho ka nahanoa hore hemostasis ea pele e ka ba molemo 'me ea thusa ho hlaphoheloa ka mor'a ho ferekana ha lesapo la mokokotlo ho likhoto.Leha ho le joalo, phello e hlahisoang ke BPC 157 e ka 'na ea fapana le phello e bonolo ea hemostatic e neng e ka fokotsa kotsi ea lesapo la mokokotlo, hobane BPC 157 e boetse e ntlafatsa ka mokhoa o hlakileng ts'ebetso ea thrombocyte ho likhoto ntle le ho ama lintlha tsa coagulation.Nakong ea ho hlaphoheloa ho tsoa kotsi ea lesapo la mokokotlo, BPC 157 e boetse e sireletsa endothelium ka ho toba, e fokotsa litšitiso tsa peripheral vascular occlusion, ka potlako e kenya tšebetsong litsela tse ling, 'me e loantšana le li-syndromes tse bakoang ke venous occlusion-induced.Ka hona, ho nka hore ho na le monehelo o moholo oa venous ho khatello ea mokokotlo oa mokokotlo, ho ka nahanoa hore phallo ea mali e tsosolositsoeng e kopanngoeng ke BPC 157 ha ho pelaelo hore e ka kenya letsoho hore ho be le phello e potlakileng ea ho hlaphoheloa.Ho feta moo, ha ho nahanoa hore BPC 157 e khothalletsa ho tsosolosoa ka ho sa feleng ka mor'a khatello ea lesapo la mokokotlo, ho lokela ho hlokomeloa hore ha BPC 157 e fanoa nakong ea ho tsosolosoa, e loantšana le setorouku se bakoang ke ho phunyeletsa ha mahlakore a mabeli a methapo e tloaelehileng ea carotid.BPC 157 e rarolla ts'enyo ea neuronal mme e thibela mohopolo, locomotor, le likhaello tsa khokahano.BPC 157 ho bonahala e fana ka litlamorao tsena ka ho fetola liphatsa tsa lefutso ho hippocampus.
Qetellong, BPC 157 e na le liphello tse molemo ho stroke, schizophrenia le lesapo la mokokotlo .
Bafuputsi ba bonts'itse khafetsa hore BPC 157 e na le litlamorao tse ngata tse molemo 'meleng.Ha ho na lebaka la ho bontša hore melemo ea BPC 157 e lekantsoe ke ho nepahala ha mefuta e sebelisitsoeng le/kapa mefokolo ea mekhoa.Ha e le hantle, re ka pheha khang ea hore katleho, ts'ebeliso e bonolo, boemo bo sireletsehileng ba kliniki le mochine oa BPC 157 li emela mokhoa o mong, mohlomong o atlehileng, tataiso ea phekolo ea nakong e tlang bakeng sa maemo a methapo ea kutlo.Ka hona, ho hlokahala lithuto tse eketsehileng ho hlakisa hore na phekolo e ka bang teng ea BPC 157 e ka sebetsana joang ka ho khetheha le mokhoa oa ts'ebetso o kenyelletsang libaka tse ngata tsa subcellular ho CNS.Tšusumetso mosebetsing oa boholo, haeba e se kaofela, litsamaiso tsa neuronal maemong a limolek'hule, cellular, le systemic li lokela ho hlahlojoa.Tse ling tsa li-visceral repetitive relay tsa CNS kapa circumventricular, e 'ngoe ea libaka tse' maloa bokong ntle le mokoallo oa boko ba mali, ke tsela e tsejoang eo peptide e tsamaisoang ka mokhoa oa tsamaiso e ka bang le phello e bohareng.Kahoo, e tlameha ho sebetsa ka har'a axis ea boko ba mala, ho sa tsotellehe hore na ketso ena e tobileng kapa e sa tobang.
